Since Foundayo arrived in the UK, one of the most common questions we hear is from people who are already on a weight loss treatment: should I switch? Some are tired of weekly injections. Some are on the Wegovy pill and find the empty-stomach routine hard to stick to. Others have reached a weight they are happy with and want a simpler way to hold on to it.
This guide sets out what the evidence actually shows about switching to Foundayo, who it tends to suit, and when staying on your current treatment is the better call. For the full overview of the treatment itself, see our complete guide to Foundayo in Swansea.
The honest headline
If you are doing well on your current treatment, there is often no need to change. But there is now good trial evidence that people who switch from an injection to Foundayo keep most of the weight they have lost. The right answer depends on why you want to switch, and that is a conversation to have with a prescriber, not a decision to make alone.
Why People Consider Switching
The reasons tend to fall into a few groups. The first is the needle. Some people never quite get used to injecting, and a daily tablet feels far easier. The second is routine. The Wegovy pill has to be taken on an empty stomach with a small sip of water and a wait before eating, which does not suit everyone’s mornings. Foundayo can be taken at any time of day, with or without food or water. The third is the long term. People who have lost weight on an injection often want to know how to keep it off, and whether a tablet could do that job.
All three are fair reasons to ask the question. None of them automatically means switching is right for you.
What the Evidence Shows
Switching is one of the few questions about Foundayo that has been tested directly. In a phase 3 trial called ATTAIN-MAINTAIN, adults who had already lost weight on the highest dose they could tolerate of either the Wegovy injection (semaglutide) or tirzepatide, the medicine in Mounjaro, were moved onto once-daily Foundayo or a placebo tablet for 52 weeks.
People who switched from the Wegovy injection to Foundayo kept, on average, about 79% of the weight they had lost, compared with about 38% for those who switched to placebo. People who switched from tirzepatide kept about 75% of their weight loss on Foundayo, compared with about 49% on placebo.
ATTAIN-MAINTAIN Trial (52 weeks after switching)
Around 79%
of weight loss kept after switching from the Wegovy injection
Versus around 38% on placebo. For people switching from tirzepatide, around 75% was kept versus around 49% on placebo. Individual results vary. Source: ATTAIN-MAINTAIN trial (Eli Lilly), published in Nature Medicine.
There are two honest points to take from that. First, Foundayo did a far better job of holding weight off than stopping treatment altogether, which is the real alternative many people face. Second, most people kept most of their weight loss, not all of it. Some weight regain is common, and it was larger on average for people coming off tirzepatide. That is worth knowing before you decide.
Who Switching Tends to Suit
Switching is most worth discussing if you have reached a weight you are happy with and want a simpler way to maintain it, if injecting has become a real barrier to staying on treatment, or if the Wegovy pill’s morning routine keeps getting in the way. In each case the aim is the same: a treatment you can actually keep taking, because the best treatment on paper is no use if you cannot stick with it.
When Staying Put Is the Better Call
If your current treatment is working, you are tolerating it well, and you are still losing weight towards your goal, there is usually no strong reason to change. The trial above looked at people who had already lost weight and were moving into maintenance, not people in the middle of their weight loss. Changing treatment mid-journey can also mean going back through a period of dose adjustment and side effects while your body gets used to a new medicine.
If what you really want is to stay on Mounjaro but change who provides it, that is a different question, and we cover it in our guide to switching your Mounjaro provider.
How Switching Works at Medihub
There is no simple conversion chart from an injection or the Wegovy pill to a Foundayo dose. These are different medicines, so your prescriber decides your starting dose and the timing of your first tablet based on what you are currently taking, how long you have been on it, how you have tolerated it and what you want to achieve. Please do not stop your current treatment or take both at the same time without speaking to a prescriber first.
At your consultation we will go through your treatment history, check your blood pressure and weight, and agree a plan. After that, each monthly review includes a face-to-face consultation, a blood pressure check and a weight check, so we can see how the switch is going and adjust if needed. Foundayo prices at Medihub run from £109 for the starting dose to £189 for the highest, and the full table is in our Foundayo guide.
Side Effects When You Switch
Foundayo belongs to the same family of medicines as Mounjaro and Wegovy, so the side effects are similar. The most common are gastrointestinal: nausea, constipation, vomiting and diarrhoea. In the switching trial, nausea and constipation were the most frequent. These are usually most noticeable early on or after a dose change, and tend to settle as your body adjusts. Your prescriber will explain what to expect and when to get in touch.
Foundayo is not suitable for everyone, including during pregnancy and breastfeeding. Your prescriber will go through your full medical history before you switch.
Why Choose Medihub
Switching treatment is exactly the kind of decision that benefits from a real conversation. At Medihub you are seen in person by a named Independent Prescriber: Osama Al-Saied at Killay, GPhC number 2222112, and Carwyn Jones at Pontarddulais, both publicly verifiable on the pharmacy regulator’s register. We will tell you honestly if we think you are better off staying where you are.
Both branches offer the same service. Killay on Gower Road, SA2 7BA, serves Killay, Sketty, West Cross and the Gower peninsula. Pontarddulais on St Teilo Street, SA4 8ST, is convenient for Pontarddulais, Gorseinon, Llansamlet and Morriston, and the wider Swansea area.
Thinking about switching to Foundayo?
Book a consultation at our Killay or Pontarddulais branch and we will talk through whether switching is right for you.
Frequently Asked Questions
Can I switch from Mounjaro to Foundayo?
Yes, it is possible. In the ATTAIN-MAINTAIN trial, people who switched from tirzepatide, the medicine in Mounjaro, to Foundayo kept around 75% of their weight loss over a year, compared with around 49% on placebo. Your prescriber will decide your starting dose and timing.
Can I switch from the Wegovy injection to Foundayo?
Yes. In the same trial, people who switched from the Wegovy injection kept around 79% of their weight loss on Foundayo, compared with around 38% on placebo.
Can I switch from the Wegovy pill to Foundayo?
A prescriber can discuss it with you, and the main practical difference is that Foundayo has no empty-stomach or water rules. There is no trial yet that has tested this particular switch, so it is a decision to make carefully with your prescriber. Our guide to Foundayo versus the Wegovy pill compares the two tablets side by side.
Will I regain weight if I switch?
Some regain is common. In the trial most people kept most of their weight loss on Foundayo, and far more than on placebo, but not all of it. Keeping up the diet and activity changes you have made makes a real difference.
Can I just start Foundayo the day after my last injection?
Please do not plan the timing yourself. Your prescriber will tell you when to take your first tablet and at what dose, based on what you are currently on. Do not take both treatments together unless your prescriber tells you to.
Can I switch to Foundayo in Swansea?
Yes. Medihub Pharmacy offers Foundayo privately at both its Swansea branches, Killay and Pontarddulais, with a face-to-face assessment and monthly reviews. No GP referral is needed to book.
Switching to Foundayo can make a lot of sense for the right person, and it is one of the few treatment changes that has been tested in its own trial. If you would like an honest view on whether it suits you, book a consultation at your nearest Swansea branch, or read our complete guide to Foundayo in Swansea first.
Reviewed and medically verified by
Osama Al-Saied, Independent Prescriber
GPhC Number: 2222112 | Independent Prescriber
Medihub Pharmacy, Killay and Pontarddulais, Swansea
Verify on the GPhC register